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- 低剂量IL-2皮下注射8周可持续增加慢性难治性移植物抗宿主病患者体内调节性T细胞数量并改善患者临床症状
Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease
New Engl J Med PubMed (1 Dec 2011) |
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- 治疗二型糖尿病新药JNJ38431055在健康男性志愿者中的药效、药代、安全性和耐受性评估
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of JNJ-38431055, a Novel GPR119 Receptor Agonist and Potential Antidiabetes Agent, in Healthy Male Subjects
Clin Pharmacol Ther PubMed (Nov 2011) |
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- 冠脉内导入自体心脏干细胞治疗缺血性心肌病的1期临床试验：疗效显著
Cardiac Stem Cells in Patients with Ischaemic Cardiomyopathy (SCIPIO): Initial Results of a Randomised Phase 1 Trial
Lancet PubMed (26 Nov 2011) |
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- 分节性动脉中膜融解症：两例病案报告及文献综述
Segmental Arterial Mediolysis: Report of 2 Cases and Review of the Literature
Am J Kidney Dis PubMed (Dec 2011) |
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- 1例不寻常但容易治疗的病因引起的急性胰腺炎病例报告：胰腺蛔虫是罪魁祸首
Acute Pancreatitis: an Uncommon but Easily Treatable Cause
Gastroenterology PubMed (Dec 2011) |
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- 2型糖尿病风险基因变异可增加结直肠癌易感性：一项多中心队列研究
Type 2 Diabetes Risk Variants and Colorectal Cancer Risk: the Multiethnic Cohort and PAGE Studies
Gut PubMed (Dec 2011) |
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- Pridopidine用于改善亨廷顿氏舞蹈病患者的运动功能: 一项随机双盲安慰剂对照的3期临床试验
Pridopidine for the Treatment of Motor Function in Patients with Huntington's disease (MermaiHD): a Phase 3, Randomised, Double-blind, Placebo-controlled Trial
Lancet Neuro PubMed (Dec 2011) |
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- 模式识别受体激动剂（人工合成的双链RNA）诱导的天然免疫水平与活病毒疫苗激发的水平相当
Synthetic Double-stranded RNA Induces Innate Immune Responses Similar to a Live Viral Vaccine in Humans
J Exp Med PubMed (21 Nov 2011) |
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- STAT3转录因子在人记忆性T细胞的发育维持和慢性病毒感染控制发挥重要作用
A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory
Immunity PubMed (23 Nov 2011) |
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- 一项大型队列研究结果表明:用于治疗儿童注意缺陷多动障碍的药物不会增加严重心血管事件的风险
ADHD Drugs and Serious Cardiovascular Events in Children and Young Adults
New Engl J Med PubMed (17 Nov 2011) |
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- 轴索麻醉较全身麻醉更有利于接受腹式子宫切除的患者术后恢复：一项前瞻性随机对照临床试验
The Effect of Neuraxial Versus General Anesthesia Techniques on Postoperative Quality of Recovery and Analgesia After Abdominal Hysterectomy: A Prospective, Randomized, Controlled Trial
Anesth Analg PubMed (Dec 2011) |
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- 自体造血干细胞移植后继以非清髓异体造血干细胞移植，并不比继以自体造血干细胞移植对多发性骨髓瘤患者疗效更好
Autologous Haemopoietic Stem-cell Transplantation Followed by Allogeneic or Autologous Haemopoietic Stem-cell Transplantation in Patients with Multiple Myeloma (BMT CTN 0102): a Phase 3 Biological Assignment Trial
Lancet Oncol PubMed (Dec 2011) |
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- 社区老年人糖尿病和偶发心力衰竭与全因死亡率相关吗？——一项倾向匹配研究
A Propensity-Matched Study of the Association of Diabetes Mellitus With Incident Heart Failure and Mortality Among Community-Dwelling Older Adults
Am J Cardiol PubMed (15 Dec 2011) |
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- 回顾性临床研究证实错误用药是导致大多数住院病人对抗凝药物出现不良反应的主要原因
Anticoagulation-associated Adverse Drug Events
Am J Med PubMed (Dec 2011) |
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- 纳米抗生素——抗生素抗药时代新曙光
“Nanoantibiotics”: A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era
J Control Release PubMed (10 Dec 2011) |
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- 临床随机对照试验表明：切割球囊法比高压血管成形术对肺动脉狭窄患者的效果更好
Randomized Trial of Cutting Balloon Compared With High-Pressure Angioplasty for the Treatment of Resistant Pulmonary Artery Stenosis
Circulation PubMed (29 Nov 2011) |
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- 综述：转录调节基因ERG——前列腺癌治疗的新靶点
Stromal Targeted Therapy in Bone Metastatic Prostate Cancer: Promise Delivered
Asian J Androl PubMed (Nov 2011) |
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- 不依赖p53的表观遗传分化治疗（地西他滨）在急性髓系白血病异体移植模型中的应用
p53 Independent Epigenetic-differentiation Treatment in Xenotransplant Models of Acute Myeloid Leukemia
Leukemia PubMed (Nov 2011) |
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- 乙肝病毒聚合酶抑制剂可轻微降低慢性乙肝患者的肾功能
Effect of HBV Polymerase Inhibitors on Renal Function in Patients with Chronic Hepatitis B
J Hepatol PubMed (Dec 2011) |
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- 出院后90天内继续使用药物预防静脉血栓栓塞不能降低患者深部静脉血栓形成或肺栓塞的发病率
Venous Thromboembolism Prophylaxis for Medical Service—Mostly Cancer—Patients at Hospital Discharge
Am J Med PubMed (Dec 2011) |
